Creating Fake Data Sets to Explore Hypotheses

Fake Hypothesis

H0: People in colder regions and warmer regions have same resilience to flu

H1: People in colder regions are more resilient to flu then people in warmer regions

For this test, will be looking at data from 2023 to 2024, for months Oct, Nov, and Dec High ILI Activity means that large proportion of patient visits are due to influenza like symptoms

In data, when assigning states, 1 = warmer region and 2 = colder region

Setting up fake data to test

# Declaring Means and Standard Deviations of samples

# mean and standard deviation will not be negative here as avg number of flu cases present should be positive, 0 at least in a wildly healthy world

mean1 = 30

stdev1 = 4

# Creating random normal samples based on means and standard deviations

flu_cases <- rnorm(100,
                   mean = mean1,
                   sd = stdev1)

flu_cases
##   [1] 25.94500 30.40664 32.49277 31.01753 32.81981 31.70585 31.09240 33.03993
##   [9] 28.13398 33.29875 29.43570 28.16660 31.42153 34.55571 25.88180 28.17306
##  [17] 32.15281 25.44768 30.47358 26.22657 35.14487 18.55346 25.43509 28.25721
##  [25] 24.88967 28.49357 32.85098 36.95344 29.92623 28.66589 27.46890 30.33376
##  [33] 25.43656 30.17890 32.70856 29.94120 38.08401 28.45616 23.17688 25.74489
##  [41] 19.79848 33.32161 31.63387 28.38589 33.95855 31.22632 27.93053 32.15667
##  [49] 33.05223 28.55207 24.06948 29.71777 31.09682 30.84369 23.44091 31.90450
##  [57] 30.96885 29.83035 36.58094 29.14035 29.89447 29.81223 27.41862 29.00572
##  [65] 36.70069 28.12139 29.81103 24.73169 34.60883 29.51554 28.53941 28.09345
##  [73] 30.93841 28.20003 31.32182 37.15756 29.12520 29.90087 32.22040 18.92187
##  [81] 33.75095 33.11342 32.74765 30.51781 33.66921 27.42130 19.66014 24.54070
##  [89] 25.21656 26.43560 26.44318 33.42566 32.18265 34.45485 33.65021 43.06998
##  [97] 29.75254 29.72114 27.46170 28.78214
# Creating data set with descriptive columns based on generated samples

flu_data <- data.frame(flu_cases)

# Randomly assign categorical
flu_data$states <- sample(c(1,2))
flu_data
##     flu_cases states
## 1    25.94500      1
## 2    30.40664      2
## 3    32.49277      1
## 4    31.01753      2
## 5    32.81981      1
## 6    31.70585      2
## 7    31.09240      1
## 8    33.03993      2
## 9    28.13398      1
## 10   33.29875      2
## 11   29.43570      1
## 12   28.16660      2
## 13   31.42153      1
## 14   34.55571      2
## 15   25.88180      1
## 16   28.17306      2
## 17   32.15281      1
## 18   25.44768      2
## 19   30.47358      1
## 20   26.22657      2
## 21   35.14487      1
## 22   18.55346      2
## 23   25.43509      1
## 24   28.25721      2
## 25   24.88967      1
## 26   28.49357      2
## 27   32.85098      1
## 28   36.95344      2
## 29   29.92623      1
## 30   28.66589      2
## 31   27.46890      1
## 32   30.33376      2
## 33   25.43656      1
## 34   30.17890      2
## 35   32.70856      1
## 36   29.94120      2
## 37   38.08401      1
## 38   28.45616      2
## 39   23.17688      1
## 40   25.74489      2
## 41   19.79848      1
## 42   33.32161      2
## 43   31.63387      1
## 44   28.38589      2
## 45   33.95855      1
## 46   31.22632      2
## 47   27.93053      1
## 48   32.15667      2
## 49   33.05223      1
## 50   28.55207      2
## 51   24.06948      1
## 52   29.71777      2
## 53   31.09682      1
## 54   30.84369      2
## 55   23.44091      1
## 56   31.90450      2
## 57   30.96885      1
## 58   29.83035      2
## 59   36.58094      1
## 60   29.14035      2
## 61   29.89447      1
## 62   29.81223      2
## 63   27.41862      1
## 64   29.00572      2
## 65   36.70069      1
## 66   28.12139      2
## 67   29.81103      1
## 68   24.73169      2
## 69   34.60883      1
## 70   29.51554      2
## 71   28.53941      1
## 72   28.09345      2
## 73   30.93841      1
## 74   28.20003      2
## 75   31.32182      1
## 76   37.15756      2
## 77   29.12520      1
## 78   29.90087      2
## 79   32.22040      1
## 80   18.92187      2
## 81   33.75095      1
## 82   33.11342      2
## 83   32.74765      1
## 84   30.51781      2
## 85   33.66921      1
## 86   27.42130      2
## 87   19.66014      1
## 88   24.54070      2
## 89   25.21656      1
## 90   26.43560      2
## 91   26.44318      1
## 92   33.42566      2
## 93   32.18265      1
## 94   34.45485      2
## 95   33.65021      1
## 96   43.06998      2
## 97   29.75254      1
## 98   29.72114      2
## 99   27.46170      1
## 100  28.78214      2
# Creating Var of data and adding that to data <- double check, unsure if he wants us to provide a var or find it

flu_data$variance <- var(flu_cases)

flu_data
##     flu_cases states variance
## 1    25.94500      1 16.42369
## 2    30.40664      2 16.42369
## 3    32.49277      1 16.42369
## 4    31.01753      2 16.42369
## 5    32.81981      1 16.42369
## 6    31.70585      2 16.42369
## 7    31.09240      1 16.42369
## 8    33.03993      2 16.42369
## 9    28.13398      1 16.42369
## 10   33.29875      2 16.42369
## 11   29.43570      1 16.42369
## 12   28.16660      2 16.42369
## 13   31.42153      1 16.42369
## 14   34.55571      2 16.42369
## 15   25.88180      1 16.42369
## 16   28.17306      2 16.42369
## 17   32.15281      1 16.42369
## 18   25.44768      2 16.42369
## 19   30.47358      1 16.42369
## 20   26.22657      2 16.42369
## 21   35.14487      1 16.42369
## 22   18.55346      2 16.42369
## 23   25.43509      1 16.42369
## 24   28.25721      2 16.42369
## 25   24.88967      1 16.42369
## 26   28.49357      2 16.42369
## 27   32.85098      1 16.42369
## 28   36.95344      2 16.42369
## 29   29.92623      1 16.42369
## 30   28.66589      2 16.42369
## 31   27.46890      1 16.42369
## 32   30.33376      2 16.42369
## 33   25.43656      1 16.42369
## 34   30.17890      2 16.42369
## 35   32.70856      1 16.42369
## 36   29.94120      2 16.42369
## 37   38.08401      1 16.42369
## 38   28.45616      2 16.42369
## 39   23.17688      1 16.42369
## 40   25.74489      2 16.42369
## 41   19.79848      1 16.42369
## 42   33.32161      2 16.42369
## 43   31.63387      1 16.42369
## 44   28.38589      2 16.42369
## 45   33.95855      1 16.42369
## 46   31.22632      2 16.42369
## 47   27.93053      1 16.42369
## 48   32.15667      2 16.42369
## 49   33.05223      1 16.42369
## 50   28.55207      2 16.42369
## 51   24.06948      1 16.42369
## 52   29.71777      2 16.42369
## 53   31.09682      1 16.42369
## 54   30.84369      2 16.42369
## 55   23.44091      1 16.42369
## 56   31.90450      2 16.42369
## 57   30.96885      1 16.42369
## 58   29.83035      2 16.42369
## 59   36.58094      1 16.42369
## 60   29.14035      2 16.42369
## 61   29.89447      1 16.42369
## 62   29.81223      2 16.42369
## 63   27.41862      1 16.42369
## 64   29.00572      2 16.42369
## 65   36.70069      1 16.42369
## 66   28.12139      2 16.42369
## 67   29.81103      1 16.42369
## 68   24.73169      2 16.42369
## 69   34.60883      1 16.42369
## 70   29.51554      2 16.42369
## 71   28.53941      1 16.42369
## 72   28.09345      2 16.42369
## 73   30.93841      1 16.42369
## 74   28.20003      2 16.42369
## 75   31.32182      1 16.42369
## 76   37.15756      2 16.42369
## 77   29.12520      1 16.42369
## 78   29.90087      2 16.42369
## 79   32.22040      1 16.42369
## 80   18.92187      2 16.42369
## 81   33.75095      1 16.42369
## 82   33.11342      2 16.42369
## 83   32.74765      1 16.42369
## 84   30.51781      2 16.42369
## 85   33.66921      1 16.42369
## 86   27.42130      2 16.42369
## 87   19.66014      1 16.42369
## 88   24.54070      2 16.42369
## 89   25.21656      1 16.42369
## 90   26.43560      2 16.42369
## 91   26.44318      1 16.42369
## 92   33.42566      2 16.42369
## 93   32.18265      1 16.42369
## 94   34.45485      2 16.42369
## 95   33.65021      1 16.42369
## 96   43.06998      2 16.42369
## 97   29.75254      1 16.42369
## 98   29.72114      2 16.42369
## 99   27.46170      1 16.42369
## 100  28.78214      2 16.42369

Performing ANOVA/Hypothesis Testing

Here we will test our fake data using ANOVA

flu_data_aov <- aov(flu_cases~states, data = flu_data)
summary(flu_data_aov)
##             Df Sum Sq Mean Sq F value Pr(>F)
## states       1    0.2   0.248   0.015  0.903
## Residuals   98 1625.7  16.589

Using for loops to test different parameters

Here we are going to set up for loops to iterate through other parameters with the data, seeing how much we need to achieve a p-value < 0.05

n = 1000
count = 0
smallest_sample_size = 0

seq_5 <- seq(1, n, by = 5)
seq_10 <- seq(1, n, by = 10)


for (i in 1:length(seq_5)) {
  flu_cases <- (rnorm(seq_5[i],
                   mean = mean1,
                   sd = stdev1))
  flu_data <- data.frame(flu_cases)
  flu_data$states <- sample(c(1,2), length(flu_cases), replace = TRUE)
  flu_data$variance <- var(flu_cases)
  
  flu_data_aov <- aov(flu_cases~states, data = flu_data)
  flu_data_sum <- summary(flu_data_aov)
  cat("\n","The sample size is ->", seq_5[i], "\n")
  cat("The p-value is ->", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
  
  if (i > 1 & count == 0) {
     if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
    smallest_sample_size = seq_5[i]
     }
  }
  
  if (i > 1) {
    if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
      count = count + 1
     cat("There is a signifact difference between colder and warmer region flu cases at a sample size of ", seq_5[i], "with a p-value of ", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
      }
    
  }
  cat("Total signifcant flu cases ", count, "out of ", i, "trials", "\n") 
  cat("Smallest sample size for significant difference", smallest_sample_size, "\n")
}
## 
##  The sample size is -> 1 
## The p-value is -> 
## Total signifcant flu cases  0 out of  1 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 6 
## The p-value is -> 0.5106948 
## Total signifcant flu cases  0 out of  2 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 11 
## The p-value is -> 0.9678323 
## Total signifcant flu cases  0 out of  3 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 16 
## The p-value is -> 0.4085059 
## Total signifcant flu cases  0 out of  4 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 21 
## The p-value is -> 0.6011326 
## Total signifcant flu cases  0 out of  5 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 26 
## The p-value is -> 0.8387038 
## Total signifcant flu cases  0 out of  6 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 31 
## The p-value is -> 0.3984864 
## Total signifcant flu cases  0 out of  7 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 36 
## The p-value is -> 0.7886645 
## Total signifcant flu cases  0 out of  8 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 41 
## The p-value is -> 0.3835959 
## Total signifcant flu cases  0 out of  9 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 46 
## The p-value is -> 0.5754333 
## Total signifcant flu cases  0 out of  10 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 51 
## The p-value is -> 0.2152835 
## Total signifcant flu cases  0 out of  11 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 56 
## The p-value is -> 0.06795712 
## Total signifcant flu cases  0 out of  12 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 61 
## The p-value is -> 0.07332116 
## Total signifcant flu cases  0 out of  13 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 66 
## The p-value is -> 0.497023 
## Total signifcant flu cases  0 out of  14 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 71 
## The p-value is -> 0.656706 
## Total signifcant flu cases  0 out of  15 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 76 
## The p-value is -> 0.5254369 
## Total signifcant flu cases  0 out of  16 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 81 
## The p-value is -> 0.4775288 
## Total signifcant flu cases  0 out of  17 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 86 
## The p-value is -> 0.5302023 
## Total signifcant flu cases  0 out of  18 trials 
## Smallest sample size for significant difference 0 
## 
##  The sample size is -> 91 
## The p-value is -> 0.02503792 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  91 with a p-value of  0.02503792 
## Total signifcant flu cases  1 out of  19 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 96 
## The p-value is -> 0.1147285 
## Total signifcant flu cases  1 out of  20 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 101 
## The p-value is -> 0.8144053 
## Total signifcant flu cases  1 out of  21 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 106 
## The p-value is -> 0.7527999 
## Total signifcant flu cases  1 out of  22 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 111 
## The p-value is -> 0.6467541 
## Total signifcant flu cases  1 out of  23 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 116 
## The p-value is -> 0.3062134 
## Total signifcant flu cases  1 out of  24 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 121 
## The p-value is -> 0.03487085 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  121 with a p-value of  0.03487085 
## Total signifcant flu cases  2 out of  25 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 126 
## The p-value is -> 0.4207727 
## Total signifcant flu cases  2 out of  26 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 131 
## The p-value is -> 0.5678886 
## Total signifcant flu cases  2 out of  27 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 136 
## The p-value is -> 0.2333495 
## Total signifcant flu cases  2 out of  28 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 141 
## The p-value is -> 0.8881648 
## Total signifcant flu cases  2 out of  29 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 146 
## The p-value is -> 0.9281794 
## Total signifcant flu cases  2 out of  30 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 151 
## The p-value is -> 0.8021779 
## Total signifcant flu cases  2 out of  31 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 156 
## The p-value is -> 0.4187272 
## Total signifcant flu cases  2 out of  32 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 161 
## The p-value is -> 0.5453381 
## Total signifcant flu cases  2 out of  33 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 166 
## The p-value is -> 0.4850372 
## Total signifcant flu cases  2 out of  34 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 171 
## The p-value is -> 0.4392078 
## Total signifcant flu cases  2 out of  35 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 176 
## The p-value is -> 0.06564739 
## Total signifcant flu cases  2 out of  36 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 181 
## The p-value is -> 0.3906675 
## Total signifcant flu cases  2 out of  37 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 186 
## The p-value is -> 0.01931325 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  186 with a p-value of  0.01931325 
## Total signifcant flu cases  3 out of  38 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 191 
## The p-value is -> 0.9979525 
## Total signifcant flu cases  3 out of  39 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 196 
## The p-value is -> 0.7716177 
## Total signifcant flu cases  3 out of  40 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 201 
## The p-value is -> 0.3254518 
## Total signifcant flu cases  3 out of  41 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 206 
## The p-value is -> 0.8850736 
## Total signifcant flu cases  3 out of  42 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 211 
## The p-value is -> 0.7853006 
## Total signifcant flu cases  3 out of  43 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 216 
## The p-value is -> 0.947301 
## Total signifcant flu cases  3 out of  44 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 221 
## The p-value is -> 0.04966684 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  221 with a p-value of  0.04966684 
## Total signifcant flu cases  4 out of  45 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 226 
## The p-value is -> 0.5299987 
## Total signifcant flu cases  4 out of  46 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 231 
## The p-value is -> 0.1256983 
## Total signifcant flu cases  4 out of  47 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 236 
## The p-value is -> 0.2881545 
## Total signifcant flu cases  4 out of  48 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 241 
## The p-value is -> 0.7436217 
## Total signifcant flu cases  4 out of  49 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 246 
## The p-value is -> 0.7762627 
## Total signifcant flu cases  4 out of  50 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 251 
## The p-value is -> 0.9562854 
## Total signifcant flu cases  4 out of  51 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 256 
## The p-value is -> 0.09890616 
## Total signifcant flu cases  4 out of  52 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 261 
## The p-value is -> 0.05326824 
## Total signifcant flu cases  4 out of  53 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 266 
## The p-value is -> 0.2542177 
## Total signifcant flu cases  4 out of  54 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 271 
## The p-value is -> 0.6137268 
## Total signifcant flu cases  4 out of  55 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 276 
## The p-value is -> 0.1253095 
## Total signifcant flu cases  4 out of  56 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 281 
## The p-value is -> 0.2816848 
## Total signifcant flu cases  4 out of  57 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 286 
## The p-value is -> 0.4686325 
## Total signifcant flu cases  4 out of  58 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 291 
## The p-value is -> 0.6513576 
## Total signifcant flu cases  4 out of  59 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 296 
## The p-value is -> 0.9860414 
## Total signifcant flu cases  4 out of  60 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 301 
## The p-value is -> 0.8053977 
## Total signifcant flu cases  4 out of  61 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 306 
## The p-value is -> 0.9316048 
## Total signifcant flu cases  4 out of  62 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 311 
## The p-value is -> 0.6178824 
## Total signifcant flu cases  4 out of  63 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 316 
## The p-value is -> 0.1002274 
## Total signifcant flu cases  4 out of  64 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 321 
## The p-value is -> 0.3103327 
## Total signifcant flu cases  4 out of  65 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 326 
## The p-value is -> 0.8201394 
## Total signifcant flu cases  4 out of  66 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 331 
## The p-value is -> 0.05230837 
## Total signifcant flu cases  4 out of  67 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 336 
## The p-value is -> 0.7237357 
## Total signifcant flu cases  4 out of  68 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 341 
## The p-value is -> 0.5079496 
## Total signifcant flu cases  4 out of  69 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 346 
## The p-value is -> 0.3235191 
## Total signifcant flu cases  4 out of  70 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 351 
## The p-value is -> 0.8067621 
## Total signifcant flu cases  4 out of  71 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 356 
## The p-value is -> 0.9560404 
## Total signifcant flu cases  4 out of  72 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 361 
## The p-value is -> 0.6781044 
## Total signifcant flu cases  4 out of  73 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 366 
## The p-value is -> 0.6962999 
## Total signifcant flu cases  4 out of  74 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 371 
## The p-value is -> 0.5918531 
## Total signifcant flu cases  4 out of  75 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 376 
## The p-value is -> 0.6987713 
## Total signifcant flu cases  4 out of  76 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 381 
## The p-value is -> 0.8988323 
## Total signifcant flu cases  4 out of  77 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 386 
## The p-value is -> 0.170895 
## Total signifcant flu cases  4 out of  78 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 391 
## The p-value is -> 0.2059382 
## Total signifcant flu cases  4 out of  79 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 396 
## The p-value is -> 0.07495393 
## Total signifcant flu cases  4 out of  80 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 401 
## The p-value is -> 0.5731249 
## Total signifcant flu cases  4 out of  81 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 406 
## The p-value is -> 0.3076082 
## Total signifcant flu cases  4 out of  82 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 411 
## The p-value is -> 0.6697683 
## Total signifcant flu cases  4 out of  83 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 416 
## The p-value is -> 0.2395966 
## Total signifcant flu cases  4 out of  84 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 421 
## The p-value is -> 0.5367502 
## Total signifcant flu cases  4 out of  85 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 426 
## The p-value is -> 0.7436752 
## Total signifcant flu cases  4 out of  86 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 431 
## The p-value is -> 0.6260414 
## Total signifcant flu cases  4 out of  87 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 436 
## The p-value is -> 0.4421753 
## Total signifcant flu cases  4 out of  88 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 441 
## The p-value is -> 0.6397151 
## Total signifcant flu cases  4 out of  89 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 446 
## The p-value is -> 0.5089551 
## Total signifcant flu cases  4 out of  90 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 451 
## The p-value is -> 0.1804405 
## Total signifcant flu cases  4 out of  91 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 456 
## The p-value is -> 0.3994684 
## Total signifcant flu cases  4 out of  92 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 461 
## The p-value is -> 0.1418152 
## Total signifcant flu cases  4 out of  93 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 466 
## The p-value is -> 0.8411136 
## Total signifcant flu cases  4 out of  94 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 471 
## The p-value is -> 0.615057 
## Total signifcant flu cases  4 out of  95 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 476 
## The p-value is -> 0.2028054 
## Total signifcant flu cases  4 out of  96 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 481 
## The p-value is -> 0.3557648 
## Total signifcant flu cases  4 out of  97 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 486 
## The p-value is -> 0.5357313 
## Total signifcant flu cases  4 out of  98 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 491 
## The p-value is -> 0.968479 
## Total signifcant flu cases  4 out of  99 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 496 
## The p-value is -> 0.2696359 
## Total signifcant flu cases  4 out of  100 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 501 
## The p-value is -> 0.5111133 
## Total signifcant flu cases  4 out of  101 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 506 
## The p-value is -> 0.8573264 
## Total signifcant flu cases  4 out of  102 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 511 
## The p-value is -> 0.6092084 
## Total signifcant flu cases  4 out of  103 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 516 
## The p-value is -> 0.05865493 
## Total signifcant flu cases  4 out of  104 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 521 
## The p-value is -> 0.9520109 
## Total signifcant flu cases  4 out of  105 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 526 
## The p-value is -> 0.9692814 
## Total signifcant flu cases  4 out of  106 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 531 
## The p-value is -> 0.0904244 
## Total signifcant flu cases  4 out of  107 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 536 
## The p-value is -> 0.7356918 
## Total signifcant flu cases  4 out of  108 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 541 
## The p-value is -> 0.152701 
## Total signifcant flu cases  4 out of  109 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 546 
## The p-value is -> 0.359567 
## Total signifcant flu cases  4 out of  110 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 551 
## The p-value is -> 0.7347299 
## Total signifcant flu cases  4 out of  111 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 556 
## The p-value is -> 0.8502083 
## Total signifcant flu cases  4 out of  112 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 561 
## The p-value is -> 0.2670028 
## Total signifcant flu cases  4 out of  113 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 566 
## The p-value is -> 0.5207071 
## Total signifcant flu cases  4 out of  114 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 571 
## The p-value is -> 0.492641 
## Total signifcant flu cases  4 out of  115 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 576 
## The p-value is -> 0.2737672 
## Total signifcant flu cases  4 out of  116 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 581 
## The p-value is -> 0.8036041 
## Total signifcant flu cases  4 out of  117 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 586 
## The p-value is -> 0.2992094 
## Total signifcant flu cases  4 out of  118 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 591 
## The p-value is -> 0.06305557 
## Total signifcant flu cases  4 out of  119 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 596 
## The p-value is -> 0.1317571 
## Total signifcant flu cases  4 out of  120 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 601 
## The p-value is -> 0.2178749 
## Total signifcant flu cases  4 out of  121 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 606 
## The p-value is -> 0.5253752 
## Total signifcant flu cases  4 out of  122 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 611 
## The p-value is -> 0.4444112 
## Total signifcant flu cases  4 out of  123 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 616 
## The p-value is -> 0.6069858 
## Total signifcant flu cases  4 out of  124 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 621 
## The p-value is -> 0.7182592 
## Total signifcant flu cases  4 out of  125 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 626 
## The p-value is -> 0.05616974 
## Total signifcant flu cases  4 out of  126 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 631 
## The p-value is -> 0.8378986 
## Total signifcant flu cases  4 out of  127 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 636 
## The p-value is -> 0.2934759 
## Total signifcant flu cases  4 out of  128 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 641 
## The p-value is -> 0.2596641 
## Total signifcant flu cases  4 out of  129 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 646 
## The p-value is -> 0.3658938 
## Total signifcant flu cases  4 out of  130 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 651 
## The p-value is -> 0.3145522 
## Total signifcant flu cases  4 out of  131 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 656 
## The p-value is -> 0.1580886 
## Total signifcant flu cases  4 out of  132 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 661 
## The p-value is -> 0.02040959 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  661 with a p-value of  0.02040959 
## Total signifcant flu cases  5 out of  133 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 666 
## The p-value is -> 0.2290797 
## Total signifcant flu cases  5 out of  134 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 671 
## The p-value is -> 0.1581163 
## Total signifcant flu cases  5 out of  135 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 676 
## The p-value is -> 0.8454443 
## Total signifcant flu cases  5 out of  136 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 681 
## The p-value is -> 0.3086262 
## Total signifcant flu cases  5 out of  137 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 686 
## The p-value is -> 0.2948475 
## Total signifcant flu cases  5 out of  138 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 691 
## The p-value is -> 0.5687653 
## Total signifcant flu cases  5 out of  139 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 696 
## The p-value is -> 0.5050774 
## Total signifcant flu cases  5 out of  140 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 701 
## The p-value is -> 0.5192124 
## Total signifcant flu cases  5 out of  141 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 706 
## The p-value is -> 0.3570631 
## Total signifcant flu cases  5 out of  142 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 711 
## The p-value is -> 0.6664561 
## Total signifcant flu cases  5 out of  143 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 716 
## The p-value is -> 0.1091425 
## Total signifcant flu cases  5 out of  144 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 721 
## The p-value is -> 0.1816518 
## Total signifcant flu cases  5 out of  145 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 726 
## The p-value is -> 0.1319489 
## Total signifcant flu cases  5 out of  146 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 731 
## The p-value is -> 0.7546288 
## Total signifcant flu cases  5 out of  147 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 736 
## The p-value is -> 0.6145865 
## Total signifcant flu cases  5 out of  148 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 741 
## The p-value is -> 0.7634528 
## Total signifcant flu cases  5 out of  149 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 746 
## The p-value is -> 0.2510106 
## Total signifcant flu cases  5 out of  150 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 751 
## The p-value is -> 0.5418623 
## Total signifcant flu cases  5 out of  151 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 756 
## The p-value is -> 0.07847847 
## Total signifcant flu cases  5 out of  152 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 761 
## The p-value is -> 0.6245795 
## Total signifcant flu cases  5 out of  153 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 766 
## The p-value is -> 0.01887014 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  766 with a p-value of  0.01887014 
## Total signifcant flu cases  6 out of  154 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 771 
## The p-value is -> 0.6545496 
## Total signifcant flu cases  6 out of  155 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 776 
## The p-value is -> 0.1010776 
## Total signifcant flu cases  6 out of  156 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 781 
## The p-value is -> 0.6185636 
## Total signifcant flu cases  6 out of  157 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 786 
## The p-value is -> 0.5080109 
## Total signifcant flu cases  6 out of  158 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 791 
## The p-value is -> 0.2840964 
## Total signifcant flu cases  6 out of  159 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 796 
## The p-value is -> 0.4109504 
## Total signifcant flu cases  6 out of  160 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 801 
## The p-value is -> 0.7990803 
## Total signifcant flu cases  6 out of  161 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 806 
## The p-value is -> 0.4422727 
## Total signifcant flu cases  6 out of  162 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 811 
## The p-value is -> 0.6440968 
## Total signifcant flu cases  6 out of  163 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 816 
## The p-value is -> 0.1358615 
## Total signifcant flu cases  6 out of  164 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 821 
## The p-value is -> 0.7975637 
## Total signifcant flu cases  6 out of  165 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 826 
## The p-value is -> 0.3256264 
## Total signifcant flu cases  6 out of  166 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 831 
## The p-value is -> 0.1920249 
## Total signifcant flu cases  6 out of  167 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 836 
## The p-value is -> 0.3861772 
## Total signifcant flu cases  6 out of  168 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 841 
## The p-value is -> 0.08849789 
## Total signifcant flu cases  6 out of  169 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 846 
## The p-value is -> 0.4551328 
## Total signifcant flu cases  6 out of  170 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 851 
## The p-value is -> 0.8441035 
## Total signifcant flu cases  6 out of  171 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 856 
## The p-value is -> 0.9195265 
## Total signifcant flu cases  6 out of  172 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 861 
## The p-value is -> 0.3389194 
## Total signifcant flu cases  6 out of  173 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 866 
## The p-value is -> 0.4966679 
## Total signifcant flu cases  6 out of  174 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 871 
## The p-value is -> 0.5930632 
## Total signifcant flu cases  6 out of  175 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 876 
## The p-value is -> 0.4325368 
## Total signifcant flu cases  6 out of  176 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 881 
## The p-value is -> 0.2617479 
## Total signifcant flu cases  6 out of  177 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 886 
## The p-value is -> 0.2590661 
## Total signifcant flu cases  6 out of  178 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 891 
## The p-value is -> 0.9018074 
## Total signifcant flu cases  6 out of  179 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 896 
## The p-value is -> 0.6781099 
## Total signifcant flu cases  6 out of  180 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 901 
## The p-value is -> 0.9542938 
## Total signifcant flu cases  6 out of  181 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 906 
## The p-value is -> 0.7687492 
## Total signifcant flu cases  6 out of  182 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 911 
## The p-value is -> 0.2554554 
## Total signifcant flu cases  6 out of  183 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 916 
## The p-value is -> 0.9820056 
## Total signifcant flu cases  6 out of  184 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 921 
## The p-value is -> 0.2589867 
## Total signifcant flu cases  6 out of  185 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 926 
## The p-value is -> 0.6439669 
## Total signifcant flu cases  6 out of  186 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 931 
## The p-value is -> 0.03162947 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  931 with a p-value of  0.03162947 
## Total signifcant flu cases  7 out of  187 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 936 
## The p-value is -> 0.1192682 
## Total signifcant flu cases  7 out of  188 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 941 
## The p-value is -> 0.5163906 
## Total signifcant flu cases  7 out of  189 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 946 
## The p-value is -> 0.7169867 
## Total signifcant flu cases  7 out of  190 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 951 
## The p-value is -> 0.5103322 
## Total signifcant flu cases  7 out of  191 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 956 
## The p-value is -> 0.3155888 
## Total signifcant flu cases  7 out of  192 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 961 
## The p-value is -> 0.5523944 
## Total signifcant flu cases  7 out of  193 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 966 
## The p-value is -> 0.8261954 
## Total signifcant flu cases  7 out of  194 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 971 
## The p-value is -> 0.7564485 
## Total signifcant flu cases  7 out of  195 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 976 
## The p-value is -> 0.4764971 
## Total signifcant flu cases  7 out of  196 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 981 
## The p-value is -> 0.5823174 
## Total signifcant flu cases  7 out of  197 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 986 
## The p-value is -> 0.5928227 
## Total signifcant flu cases  7 out of  198 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 991 
## The p-value is -> 0.9404265 
## Total signifcant flu cases  7 out of  199 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 996 
## The p-value is -> 0.4279822 
## Total signifcant flu cases  7 out of  200 trials 
## Smallest sample size for significant difference 91
# Need to reset counter for each loop
count = 0

for (i in 1:length(seq_10)) {
  flu_cases <- (rnorm(seq_10[i],
                   mean = mean1,
                   sd = stdev1))
  flu_data <- data.frame(flu_cases)
  flu_data$states <- sample(c(1,2), length(flu_cases), replace = TRUE)
  flu_data$variance <- var(flu_cases)
  
  flu_data_aov <- aov(flu_cases~states, data = flu_data)
  flu_data_sum <- summary(flu_data_aov)
  cat("\n","The sample size is ->", seq_10[i], "\n")
  cat("The p-value is ->", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
  
  if (i > 1 & count == 0) {
     if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
    smallest_sample_size = seq_10[i]
     }
  }
  
 if (i > 1) {
    if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
    count = count + 1
     cat("There is a signifact difference between colder and warmer region flu cases at a sample size of ", seq_10[i], "with a p-value of ", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
      }
    
  }
  cat("Total signifcant flu cases ", count, "out of ", i, "trials", "\n")
  cat("Smallest sample size for significant difference", smallest_sample_size, "\n")
} 
## 
##  The sample size is -> 1 
## The p-value is -> 
## Total signifcant flu cases  0 out of  1 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 11 
## The p-value is -> 0.6000062 
## Total signifcant flu cases  0 out of  2 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 21 
## The p-value is -> 0.7787037 
## Total signifcant flu cases  0 out of  3 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 31 
## The p-value is -> 0.2524321 
## Total signifcant flu cases  0 out of  4 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 41 
## The p-value is -> 0.7109421 
## Total signifcant flu cases  0 out of  5 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 51 
## The p-value is -> 0.7003825 
## Total signifcant flu cases  0 out of  6 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 61 
## The p-value is -> 0.3687309 
## Total signifcant flu cases  0 out of  7 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 71 
## The p-value is -> 0.4981922 
## Total signifcant flu cases  0 out of  8 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 81 
## The p-value is -> 0.6088305 
## Total signifcant flu cases  0 out of  9 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 91 
## The p-value is -> 0.6465656 
## Total signifcant flu cases  0 out of  10 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 101 
## The p-value is -> 0.4621256 
## Total signifcant flu cases  0 out of  11 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 111 
## The p-value is -> 0.9946152 
## Total signifcant flu cases  0 out of  12 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 121 
## The p-value is -> 0.616271 
## Total signifcant flu cases  0 out of  13 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 131 
## The p-value is -> 0.728792 
## Total signifcant flu cases  0 out of  14 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 141 
## The p-value is -> 0.2373934 
## Total signifcant flu cases  0 out of  15 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 151 
## The p-value is -> 0.7902918 
## Total signifcant flu cases  0 out of  16 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 161 
## The p-value is -> 0.7641848 
## Total signifcant flu cases  0 out of  17 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 171 
## The p-value is -> 0.1685983 
## Total signifcant flu cases  0 out of  18 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 181 
## The p-value is -> 0.08508033 
## Total signifcant flu cases  0 out of  19 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 191 
## The p-value is -> 0.9709528 
## Total signifcant flu cases  0 out of  20 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 201 
## The p-value is -> 0.6213549 
## Total signifcant flu cases  0 out of  21 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 211 
## The p-value is -> 0.1817231 
## Total signifcant flu cases  0 out of  22 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 221 
## The p-value is -> 0.3652502 
## Total signifcant flu cases  0 out of  23 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 231 
## The p-value is -> 0.4354472 
## Total signifcant flu cases  0 out of  24 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 241 
## The p-value is -> 0.9010818 
## Total signifcant flu cases  0 out of  25 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 251 
## The p-value is -> 0.9220202 
## Total signifcant flu cases  0 out of  26 trials 
## Smallest sample size for significant difference 91 
## 
##  The sample size is -> 261 
## The p-value is -> 0.03622272 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  261 with a p-value of  0.03622272 
## Total signifcant flu cases  1 out of  27 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 271 
## The p-value is -> 0.9701471 
## Total signifcant flu cases  1 out of  28 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 281 
## The p-value is -> 0.4587492 
## Total signifcant flu cases  1 out of  29 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 291 
## The p-value is -> 0.6293383 
## Total signifcant flu cases  1 out of  30 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 301 
## The p-value is -> 0.7282301 
## Total signifcant flu cases  1 out of  31 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 311 
## The p-value is -> 0.02316597 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  311 with a p-value of  0.02316597 
## Total signifcant flu cases  2 out of  32 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 321 
## The p-value is -> 0.9758291 
## Total signifcant flu cases  2 out of  33 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 331 
## The p-value is -> 0.06369116 
## Total signifcant flu cases  2 out of  34 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 341 
## The p-value is -> 0.200242 
## Total signifcant flu cases  2 out of  35 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 351 
## The p-value is -> 0.597222 
## Total signifcant flu cases  2 out of  36 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 361 
## The p-value is -> 0.9420939 
## Total signifcant flu cases  2 out of  37 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 371 
## The p-value is -> 0.7685948 
## Total signifcant flu cases  2 out of  38 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 381 
## The p-value is -> 0.576229 
## Total signifcant flu cases  2 out of  39 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 391 
## The p-value is -> 0.8202309 
## Total signifcant flu cases  2 out of  40 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 401 
## The p-value is -> 0.5821382 
## Total signifcant flu cases  2 out of  41 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 411 
## The p-value is -> 0.1764276 
## Total signifcant flu cases  2 out of  42 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 421 
## The p-value is -> 0.2396096 
## Total signifcant flu cases  2 out of  43 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 431 
## The p-value is -> 0.6806384 
## Total signifcant flu cases  2 out of  44 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 441 
## The p-value is -> 0.7633106 
## Total signifcant flu cases  2 out of  45 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 451 
## The p-value is -> 0.6658355 
## Total signifcant flu cases  2 out of  46 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 461 
## The p-value is -> 0.888849 
## Total signifcant flu cases  2 out of  47 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 471 
## The p-value is -> 0.9457109 
## Total signifcant flu cases  2 out of  48 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 481 
## The p-value is -> 0.001490146 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  481 with a p-value of  0.001490146 
## Total signifcant flu cases  3 out of  49 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 491 
## The p-value is -> 0.1437149 
## Total signifcant flu cases  3 out of  50 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 501 
## The p-value is -> 0.1735532 
## Total signifcant flu cases  3 out of  51 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 511 
## The p-value is -> 0.2617107 
## Total signifcant flu cases  3 out of  52 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 521 
## The p-value is -> 0.5535551 
## Total signifcant flu cases  3 out of  53 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 531 
## The p-value is -> 0.1505312 
## Total signifcant flu cases  3 out of  54 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 541 
## The p-value is -> 0.5536441 
## Total signifcant flu cases  3 out of  55 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 551 
## The p-value is -> 0.2826596 
## Total signifcant flu cases  3 out of  56 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 561 
## The p-value is -> 0.1209141 
## Total signifcant flu cases  3 out of  57 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 571 
## The p-value is -> 0.2798639 
## Total signifcant flu cases  3 out of  58 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 581 
## The p-value is -> 0.6147583 
## Total signifcant flu cases  3 out of  59 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 591 
## The p-value is -> 0.04087035 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  591 with a p-value of  0.04087035 
## Total signifcant flu cases  4 out of  60 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 601 
## The p-value is -> 0.1607043 
## Total signifcant flu cases  4 out of  61 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 611 
## The p-value is -> 0.8797387 
## Total signifcant flu cases  4 out of  62 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 621 
## The p-value is -> 0.4454981 
## Total signifcant flu cases  4 out of  63 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 631 
## The p-value is -> 0.2620585 
## Total signifcant flu cases  4 out of  64 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 641 
## The p-value is -> 0.6169533 
## Total signifcant flu cases  4 out of  65 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 651 
## The p-value is -> 0.7777665 
## Total signifcant flu cases  4 out of  66 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 661 
## The p-value is -> 0.6387247 
## Total signifcant flu cases  4 out of  67 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 671 
## The p-value is -> 0.8508544 
## Total signifcant flu cases  4 out of  68 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 681 
## The p-value is -> 0.9271148 
## Total signifcant flu cases  4 out of  69 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 691 
## The p-value is -> 0.9143808 
## Total signifcant flu cases  4 out of  70 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 701 
## The p-value is -> 0.4637091 
## Total signifcant flu cases  4 out of  71 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 711 
## The p-value is -> 0.9104159 
## Total signifcant flu cases  4 out of  72 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 721 
## The p-value is -> 0.7023564 
## Total signifcant flu cases  4 out of  73 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 731 
## The p-value is -> 0.6963047 
## Total signifcant flu cases  4 out of  74 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 741 
## The p-value is -> 0.07948798 
## Total signifcant flu cases  4 out of  75 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 751 
## The p-value is -> 0.1467055 
## Total signifcant flu cases  4 out of  76 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 761 
## The p-value is -> 0.5406979 
## Total signifcant flu cases  4 out of  77 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 771 
## The p-value is -> 0.2542753 
## Total signifcant flu cases  4 out of  78 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 781 
## The p-value is -> 0.9738273 
## Total signifcant flu cases  4 out of  79 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 791 
## The p-value is -> 0.7329897 
## Total signifcant flu cases  4 out of  80 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 801 
## The p-value is -> 0.0989951 
## Total signifcant flu cases  4 out of  81 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 811 
## The p-value is -> 0.3528761 
## Total signifcant flu cases  4 out of  82 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 821 
## The p-value is -> 0.5697599 
## Total signifcant flu cases  4 out of  83 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 831 
## The p-value is -> 0.7985076 
## Total signifcant flu cases  4 out of  84 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 841 
## The p-value is -> 0.9462743 
## Total signifcant flu cases  4 out of  85 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 851 
## The p-value is -> 0.03658198 
## There is a signifact difference between colder and warmer region flu cases at a sample size of  851 with a p-value of  0.03658198 
## Total signifcant flu cases  5 out of  86 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 861 
## The p-value is -> 0.4474592 
## Total signifcant flu cases  5 out of  87 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 871 
## The p-value is -> 0.1753096 
## Total signifcant flu cases  5 out of  88 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 881 
## The p-value is -> 0.2201427 
## Total signifcant flu cases  5 out of  89 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 891 
## The p-value is -> 0.3347701 
## Total signifcant flu cases  5 out of  90 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 901 
## The p-value is -> 0.2700708 
## Total signifcant flu cases  5 out of  91 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 911 
## The p-value is -> 0.2506011 
## Total signifcant flu cases  5 out of  92 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 921 
## The p-value is -> 0.1462292 
## Total signifcant flu cases  5 out of  93 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 931 
## The p-value is -> 0.08101955 
## Total signifcant flu cases  5 out of  94 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 941 
## The p-value is -> 0.9716899 
## Total signifcant flu cases  5 out of  95 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 951 
## The p-value is -> 0.1785673 
## Total signifcant flu cases  5 out of  96 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 961 
## The p-value is -> 0.2597192 
## Total signifcant flu cases  5 out of  97 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 971 
## The p-value is -> 0.1183305 
## Total signifcant flu cases  5 out of  98 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 981 
## The p-value is -> 0.9302266 
## Total signifcant flu cases  5 out of  99 trials 
## Smallest sample size for significant difference 261 
## 
##  The sample size is -> 991 
## The p-value is -> 0.3464314 
## Total signifcant flu cases  5 out of  100 trials 
## Smallest sample size for significant difference 261

Here we can see that as we alter the sample size and iterate through different sample sizes, we get close to having significant differences but it is not likely to happen (about 5 - 15% of the time). Now we will use loops to alter Mean and Standard Deviation to see if we can get significant changes.

First we will look at the mean:

n = 1000
count = 0
smallest_mean_size = 0

seq_5 <- seq(1, n, by = 5)
seq_10 <- seq(1, n, by = 10)


for (i in 1:length(seq_5)) {
  flu_cases <- (rnorm(n,
                   mean = seq_5[i],
                   sd = stdev1))
  flu_data <- data.frame(flu_cases)
  flu_data$states <- sample(c(1,2), length(flu_cases), replace = TRUE)
  flu_data$variance <- var(flu_cases)
  
  flu_data_aov <- aov(flu_cases~states, data = flu_data)
  flu_data_sum <- summary(flu_data_aov)
  cat("\n","The mean is ->", seq_5[i], "\n")
  cat("The p-value is ->", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
  
  if (i > 1 & count == 0) {
     if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
    smallest_mean_size = seq_5[i]
     }
  }
  
  if (i > 1) {
    if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
      count = count + 1
     cat("There is a signifact difference between colder and warmer region flu cases at a mean value of ", seq_5[i], "with a p-value of ", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
      }
    
  }
  cat("Total signifcant flu cases ", count, "out of ", i, "trials", "\n") 
  cat("Smallest mean for significant difference", smallest_mean_size, "\n")
}
## 
##  The mean is -> 1 
## The p-value is -> 0.6294092 
## Total signifcant flu cases  0 out of  1 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 6 
## The p-value is -> 0.0980738 
## Total signifcant flu cases  0 out of  2 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 11 
## The p-value is -> 0.108941 
## Total signifcant flu cases  0 out of  3 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 16 
## The p-value is -> 0.2211129 
## Total signifcant flu cases  0 out of  4 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 21 
## The p-value is -> 0.9028631 
## Total signifcant flu cases  0 out of  5 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 26 
## The p-value is -> 0.4330346 
## Total signifcant flu cases  0 out of  6 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 31 
## The p-value is -> 0.6138268 
## Total signifcant flu cases  0 out of  7 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 36 
## The p-value is -> 0.4208079 
## Total signifcant flu cases  0 out of  8 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 41 
## The p-value is -> 0.4592023 
## Total signifcant flu cases  0 out of  9 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 46 
## The p-value is -> 0.09139908 
## Total signifcant flu cases  0 out of  10 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 51 
## The p-value is -> 0.2676931 
## Total signifcant flu cases  0 out of  11 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 56 
## The p-value is -> 0.4591053 
## Total signifcant flu cases  0 out of  12 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 61 
## The p-value is -> 0.7648518 
## Total signifcant flu cases  0 out of  13 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 66 
## The p-value is -> 0.3355406 
## Total signifcant flu cases  0 out of  14 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 71 
## The p-value is -> 0.3780525 
## Total signifcant flu cases  0 out of  15 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 76 
## The p-value is -> 0.7127179 
## Total signifcant flu cases  0 out of  16 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 81 
## The p-value is -> 0.1870674 
## Total signifcant flu cases  0 out of  17 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 86 
## The p-value is -> 0.3655113 
## Total signifcant flu cases  0 out of  18 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 91 
## The p-value is -> 0.3582473 
## Total signifcant flu cases  0 out of  19 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 96 
## The p-value is -> 0.9744462 
## Total signifcant flu cases  0 out of  20 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 101 
## The p-value is -> 0.3478826 
## Total signifcant flu cases  0 out of  21 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 106 
## The p-value is -> 0.9057021 
## Total signifcant flu cases  0 out of  22 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 111 
## The p-value is -> 0.397738 
## Total signifcant flu cases  0 out of  23 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 116 
## The p-value is -> 0.3002333 
## Total signifcant flu cases  0 out of  24 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 121 
## The p-value is -> 0.0967691 
## Total signifcant flu cases  0 out of  25 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 126 
## The p-value is -> 0.7028098 
## Total signifcant flu cases  0 out of  26 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 131 
## The p-value is -> 0.5520364 
## Total signifcant flu cases  0 out of  27 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 136 
## The p-value is -> 0.5219789 
## Total signifcant flu cases  0 out of  28 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 141 
## The p-value is -> 0.4227854 
## Total signifcant flu cases  0 out of  29 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 146 
## The p-value is -> 0.595814 
## Total signifcant flu cases  0 out of  30 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 151 
## The p-value is -> 0.3186232 
## Total signifcant flu cases  0 out of  31 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 156 
## The p-value is -> 0.4729749 
## Total signifcant flu cases  0 out of  32 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 161 
## The p-value is -> 0.9518259 
## Total signifcant flu cases  0 out of  33 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 166 
## The p-value is -> 0.9753226 
## Total signifcant flu cases  0 out of  34 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 171 
## The p-value is -> 0.6323891 
## Total signifcant flu cases  0 out of  35 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 176 
## The p-value is -> 0.1078136 
## Total signifcant flu cases  0 out of  36 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 181 
## The p-value is -> 0.1877873 
## Total signifcant flu cases  0 out of  37 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 186 
## The p-value is -> 0.9683209 
## Total signifcant flu cases  0 out of  38 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 191 
## The p-value is -> 0.9194659 
## Total signifcant flu cases  0 out of  39 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 196 
## The p-value is -> 0.3832199 
## Total signifcant flu cases  0 out of  40 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 201 
## The p-value is -> 0.06087828 
## Total signifcant flu cases  0 out of  41 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 206 
## The p-value is -> 0.8846775 
## Total signifcant flu cases  0 out of  42 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 211 
## The p-value is -> 0.4083054 
## Total signifcant flu cases  0 out of  43 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 216 
## The p-value is -> 0.1897492 
## Total signifcant flu cases  0 out of  44 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 221 
## The p-value is -> 0.5110704 
## Total signifcant flu cases  0 out of  45 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 226 
## The p-value is -> 0.6983069 
## Total signifcant flu cases  0 out of  46 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 231 
## The p-value is -> 0.9133948 
## Total signifcant flu cases  0 out of  47 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 236 
## The p-value is -> 0.2576413 
## Total signifcant flu cases  0 out of  48 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 241 
## The p-value is -> 0.869415 
## Total signifcant flu cases  0 out of  49 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 246 
## The p-value is -> 0.453628 
## Total signifcant flu cases  0 out of  50 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 251 
## The p-value is -> 0.2161361 
## Total signifcant flu cases  0 out of  51 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 256 
## The p-value is -> 0.9613764 
## Total signifcant flu cases  0 out of  52 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 261 
## The p-value is -> 0.3931404 
## Total signifcant flu cases  0 out of  53 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 266 
## The p-value is -> 0.1992096 
## Total signifcant flu cases  0 out of  54 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 271 
## The p-value is -> 0.7340795 
## Total signifcant flu cases  0 out of  55 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 276 
## The p-value is -> 0.6994924 
## Total signifcant flu cases  0 out of  56 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 281 
## The p-value is -> 0.8771581 
## Total signifcant flu cases  0 out of  57 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 286 
## The p-value is -> 0.3552992 
## Total signifcant flu cases  0 out of  58 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 291 
## The p-value is -> 0.2446058 
## Total signifcant flu cases  0 out of  59 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 296 
## The p-value is -> 0.2891482 
## Total signifcant flu cases  0 out of  60 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 301 
## The p-value is -> 0.148242 
## Total signifcant flu cases  0 out of  61 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 306 
## The p-value is -> 0.6094669 
## Total signifcant flu cases  0 out of  62 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 311 
## The p-value is -> 0.5820897 
## Total signifcant flu cases  0 out of  63 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 316 
## The p-value is -> 0.1208716 
## Total signifcant flu cases  0 out of  64 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 321 
## The p-value is -> 0.4013024 
## Total signifcant flu cases  0 out of  65 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 326 
## The p-value is -> 0.9157896 
## Total signifcant flu cases  0 out of  66 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 331 
## The p-value is -> 0.288315 
## Total signifcant flu cases  0 out of  67 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 336 
## The p-value is -> 0.6567135 
## Total signifcant flu cases  0 out of  68 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 341 
## The p-value is -> 0.9133032 
## Total signifcant flu cases  0 out of  69 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 346 
## The p-value is -> 0.9096135 
## Total signifcant flu cases  0 out of  70 trials 
## Smallest mean for significant difference 0 
## 
##  The mean is -> 351 
## The p-value is -> 0.03094406 
## There is a signifact difference between colder and warmer region flu cases at a mean value of  351 with a p-value of  0.03094406 
## Total signifcant flu cases  1 out of  71 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 356 
## The p-value is -> 0.1958136 
## Total signifcant flu cases  1 out of  72 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 361 
## The p-value is -> 0.1174663 
## Total signifcant flu cases  1 out of  73 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 366 
## The p-value is -> 0.5644649 
## Total signifcant flu cases  1 out of  74 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 371 
## The p-value is -> 0.8267449 
## Total signifcant flu cases  1 out of  75 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 376 
## The p-value is -> 0.3378817 
## Total signifcant flu cases  1 out of  76 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 381 
## The p-value is -> 0.07584788 
## Total signifcant flu cases  1 out of  77 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 386 
## The p-value is -> 0.4342604 
## Total signifcant flu cases  1 out of  78 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 391 
## The p-value is -> 0.375363 
## Total signifcant flu cases  1 out of  79 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 396 
## The p-value is -> 0.1784625 
## Total signifcant flu cases  1 out of  80 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 401 
## The p-value is -> 0.4967869 
## Total signifcant flu cases  1 out of  81 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 406 
## The p-value is -> 0.4209707 
## Total signifcant flu cases  1 out of  82 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 411 
## The p-value is -> 0.4153493 
## Total signifcant flu cases  1 out of  83 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 416 
## The p-value is -> 0.481055 
## Total signifcant flu cases  1 out of  84 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 421 
## The p-value is -> 0.05203791 
## Total signifcant flu cases  1 out of  85 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 426 
## The p-value is -> 0.2457755 
## Total signifcant flu cases  1 out of  86 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 431 
## The p-value is -> 0.2179357 
## Total signifcant flu cases  1 out of  87 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 436 
## The p-value is -> 0.3625287 
## Total signifcant flu cases  1 out of  88 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 441 
## The p-value is -> 0.2365123 
## Total signifcant flu cases  1 out of  89 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 446 
## The p-value is -> 0.7737081 
## Total signifcant flu cases  1 out of  90 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 451 
## The p-value is -> 0.9713704 
## Total signifcant flu cases  1 out of  91 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 456 
## The p-value is -> 0.2266247 
## Total signifcant flu cases  1 out of  92 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 461 
## The p-value is -> 0.8067724 
## Total signifcant flu cases  1 out of  93 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 466 
## The p-value is -> 0.4960461 
## Total signifcant flu cases  1 out of  94 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 471 
## The p-value is -> 0.8767869 
## Total signifcant flu cases  1 out of  95 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 476 
## The p-value is -> 0.5899058 
## Total signifcant flu cases  1 out of  96 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 481 
## The p-value is -> 0.4063524 
## Total signifcant flu cases  1 out of  97 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 486 
## The p-value is -> 0.9084474 
## Total signifcant flu cases  1 out of  98 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 491 
## The p-value is -> 0.1589016 
## Total signifcant flu cases  1 out of  99 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 496 
## The p-value is -> 0.8924491 
## Total signifcant flu cases  1 out of  100 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 501 
## The p-value is -> 0.6009671 
## Total signifcant flu cases  1 out of  101 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 506 
## The p-value is -> 0.3681754 
## Total signifcant flu cases  1 out of  102 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 511 
## The p-value is -> 0.980482 
## Total signifcant flu cases  1 out of  103 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 516 
## The p-value is -> 0.8223378 
## Total signifcant flu cases  1 out of  104 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 521 
## The p-value is -> 0.2849494 
## Total signifcant flu cases  1 out of  105 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 526 
## The p-value is -> 0.2319742 
## Total signifcant flu cases  1 out of  106 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 531 
## The p-value is -> 0.08707715 
## Total signifcant flu cases  1 out of  107 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 536 
## The p-value is -> 0.6762076 
## Total signifcant flu cases  1 out of  108 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 541 
## The p-value is -> 0.8592928 
## Total signifcant flu cases  1 out of  109 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 546 
## The p-value is -> 0.1791758 
## Total signifcant flu cases  1 out of  110 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 551 
## The p-value is -> 0.9222941 
## Total signifcant flu cases  1 out of  111 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 556 
## The p-value is -> 0.8970039 
## Total signifcant flu cases  1 out of  112 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 561 
## The p-value is -> 0.993143 
## Total signifcant flu cases  1 out of  113 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 566 
## The p-value is -> 0.4907093 
## Total signifcant flu cases  1 out of  114 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 571 
## The p-value is -> 0.5829258 
## Total signifcant flu cases  1 out of  115 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 576 
## The p-value is -> 0.1837719 
## Total signifcant flu cases  1 out of  116 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 581 
## The p-value is -> 0.8866689 
## Total signifcant flu cases  1 out of  117 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 586 
## The p-value is -> 0.4113946 
## Total signifcant flu cases  1 out of  118 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 591 
## The p-value is -> 0.8588362 
## Total signifcant flu cases  1 out of  119 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 596 
## The p-value is -> 0.5917008 
## Total signifcant flu cases  1 out of  120 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 601 
## The p-value is -> 0.207668 
## Total signifcant flu cases  1 out of  121 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 606 
## The p-value is -> 0.1583368 
## Total signifcant flu cases  1 out of  122 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 611 
## The p-value is -> 0.473294 
## Total signifcant flu cases  1 out of  123 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 616 
## The p-value is -> 0.6441086 
## Total signifcant flu cases  1 out of  124 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 621 
## The p-value is -> 0.2096791 
## Total signifcant flu cases  1 out of  125 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 626 
## The p-value is -> 0.3853782 
## Total signifcant flu cases  1 out of  126 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 631 
## The p-value is -> 0.5523691 
## Total signifcant flu cases  1 out of  127 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 636 
## The p-value is -> 0.6525928 
## Total signifcant flu cases  1 out of  128 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 641 
## The p-value is -> 0.6889215 
## Total signifcant flu cases  1 out of  129 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 646 
## The p-value is -> 0.05050328 
## Total signifcant flu cases  1 out of  130 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 651 
## The p-value is -> 0.09358994 
## Total signifcant flu cases  1 out of  131 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 656 
## The p-value is -> 0.6500115 
## Total signifcant flu cases  1 out of  132 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 661 
## The p-value is -> 0.03102176 
## There is a signifact difference between colder and warmer region flu cases at a mean value of  661 with a p-value of  0.03102176 
## Total signifcant flu cases  2 out of  133 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 666 
## The p-value is -> 0.6341848 
## Total signifcant flu cases  2 out of  134 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 671 
## The p-value is -> 0.7940603 
## Total signifcant flu cases  2 out of  135 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 676 
## The p-value is -> 0.7690327 
## Total signifcant flu cases  2 out of  136 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 681 
## The p-value is -> 0.5267041 
## Total signifcant flu cases  2 out of  137 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 686 
## The p-value is -> 0.4410342 
## Total signifcant flu cases  2 out of  138 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 691 
## The p-value is -> 0.7961298 
## Total signifcant flu cases  2 out of  139 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 696 
## The p-value is -> 0.06540886 
## Total signifcant flu cases  2 out of  140 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 701 
## The p-value is -> 0.2339643 
## Total signifcant flu cases  2 out of  141 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 706 
## The p-value is -> 0.4265065 
## Total signifcant flu cases  2 out of  142 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 711 
## The p-value is -> 0.9823478 
## Total signifcant flu cases  2 out of  143 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 716 
## The p-value is -> 0.6066509 
## Total signifcant flu cases  2 out of  144 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 721 
## The p-value is -> 0.0445174 
## There is a signifact difference between colder and warmer region flu cases at a mean value of  721 with a p-value of  0.0445174 
## Total signifcant flu cases  3 out of  145 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 726 
## The p-value is -> 0.6315536 
## Total signifcant flu cases  3 out of  146 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 731 
## The p-value is -> 0.1654869 
## Total signifcant flu cases  3 out of  147 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 736 
## The p-value is -> 0.4369637 
## Total signifcant flu cases  3 out of  148 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 741 
## The p-value is -> 0.3233097 
## Total signifcant flu cases  3 out of  149 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 746 
## The p-value is -> 0.7068512 
## Total signifcant flu cases  3 out of  150 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 751 
## The p-value is -> 0.1700876 
## Total signifcant flu cases  3 out of  151 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 756 
## The p-value is -> 0.4558587 
## Total signifcant flu cases  3 out of  152 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 761 
## The p-value is -> 0.5414984 
## Total signifcant flu cases  3 out of  153 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 766 
## The p-value is -> 0.5236461 
## Total signifcant flu cases  3 out of  154 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 771 
## The p-value is -> 0.5490883 
## Total signifcant flu cases  3 out of  155 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 776 
## The p-value is -> 0.8251093 
## Total signifcant flu cases  3 out of  156 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 781 
## The p-value is -> 0.3934739 
## Total signifcant flu cases  3 out of  157 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 786 
## The p-value is -> 0.008203447 
## There is a signifact difference between colder and warmer region flu cases at a mean value of  786 with a p-value of  0.008203447 
## Total signifcant flu cases  4 out of  158 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 791 
## The p-value is -> 0.9649499 
## Total signifcant flu cases  4 out of  159 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 796 
## The p-value is -> 0.3532289 
## Total signifcant flu cases  4 out of  160 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 801 
## The p-value is -> 0.4986937 
## Total signifcant flu cases  4 out of  161 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 806 
## The p-value is -> 0.7728943 
## Total signifcant flu cases  4 out of  162 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 811 
## The p-value is -> 0.7754159 
## Total signifcant flu cases  4 out of  163 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 816 
## The p-value is -> 0.1946631 
## Total signifcant flu cases  4 out of  164 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 821 
## The p-value is -> 0.90411 
## Total signifcant flu cases  4 out of  165 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 826 
## The p-value is -> 0.2390831 
## Total signifcant flu cases  4 out of  166 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 831 
## The p-value is -> 0.5747001 
## Total signifcant flu cases  4 out of  167 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 836 
## The p-value is -> 0.6838151 
## Total signifcant flu cases  4 out of  168 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 841 
## The p-value is -> 0.1553447 
## Total signifcant flu cases  4 out of  169 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 846 
## The p-value is -> 0.4016984 
## Total signifcant flu cases  4 out of  170 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 851 
## The p-value is -> 0.125751 
## Total signifcant flu cases  4 out of  171 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 856 
## The p-value is -> 0.7949279 
## Total signifcant flu cases  4 out of  172 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 861 
## The p-value is -> 0.1946302 
## Total signifcant flu cases  4 out of  173 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 866 
## The p-value is -> 0.7585338 
## Total signifcant flu cases  4 out of  174 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 871 
## The p-value is -> 0.7105475 
## Total signifcant flu cases  4 out of  175 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 876 
## The p-value is -> 0.249202 
## Total signifcant flu cases  4 out of  176 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 881 
## The p-value is -> 0.03246643 
## There is a signifact difference between colder and warmer region flu cases at a mean value of  881 with a p-value of  0.03246643 
## Total signifcant flu cases  5 out of  177 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 886 
## The p-value is -> 0.3602979 
## Total signifcant flu cases  5 out of  178 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 891 
## The p-value is -> 0.8059529 
## Total signifcant flu cases  5 out of  179 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 896 
## The p-value is -> 0.4433425 
## Total signifcant flu cases  5 out of  180 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 901 
## The p-value is -> 0.4691468 
## Total signifcant flu cases  5 out of  181 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 906 
## The p-value is -> 0.1618057 
## Total signifcant flu cases  5 out of  182 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 911 
## The p-value is -> 0.9151926 
## Total signifcant flu cases  5 out of  183 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 916 
## The p-value is -> 0.1039725 
## Total signifcant flu cases  5 out of  184 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 921 
## The p-value is -> 0.1184916 
## Total signifcant flu cases  5 out of  185 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 926 
## The p-value is -> 0.3206211 
## Total signifcant flu cases  5 out of  186 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 931 
## The p-value is -> 0.8373892 
## Total signifcant flu cases  5 out of  187 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 936 
## The p-value is -> 0.4638345 
## Total signifcant flu cases  5 out of  188 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 941 
## The p-value is -> 0.8149721 
## Total signifcant flu cases  5 out of  189 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 946 
## The p-value is -> 0.02805346 
## There is a signifact difference between colder and warmer region flu cases at a mean value of  946 with a p-value of  0.02805346 
## Total signifcant flu cases  6 out of  190 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 951 
## The p-value is -> 0.9520372 
## Total signifcant flu cases  6 out of  191 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 956 
## The p-value is -> 0.1866317 
## Total signifcant flu cases  6 out of  192 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 961 
## The p-value is -> 0.2892103 
## Total signifcant flu cases  6 out of  193 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 966 
## The p-value is -> 0.7793073 
## Total signifcant flu cases  6 out of  194 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 971 
## The p-value is -> 0.5052709 
## Total signifcant flu cases  6 out of  195 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 976 
## The p-value is -> 0.1825231 
## Total signifcant flu cases  6 out of  196 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 981 
## The p-value is -> 0.08535514 
## Total signifcant flu cases  6 out of  197 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 986 
## The p-value is -> 0.9837567 
## Total signifcant flu cases  6 out of  198 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 991 
## The p-value is -> 0.3225141 
## Total signifcant flu cases  6 out of  199 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 996 
## The p-value is -> 0.1574491 
## Total signifcant flu cases  6 out of  200 trials 
## Smallest mean for significant difference 351
count = 0

for (i in 1:length(seq_10)) {
  flu_cases <- (rnorm(n,
                   mean = seq_10[i],
                   sd = stdev1))
  flu_data <- data.frame(flu_cases)
  flu_data$states <- sample(c(1,2), length(flu_cases), replace = TRUE)
  flu_data$variance <- var(flu_cases)
  
  flu_data_aov <- aov(flu_cases~states, data = flu_data)
  flu_data_sum <- summary(flu_data_aov)
  cat("\n","The mean is ->", seq_10[i], "\n")
  cat("The p-value is ->", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
  
  if (i > 1) {
    if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
      count = count + 1
     cat("There is a signifact difference between colder and warmer region flu cases at a mean value of ", seq_10[i], "with a p-value of ", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
      }
    
  }
  cat("Total signifcant flu cases ", count, "out of ", i, "trials", "\n") 
  cat("Smallest mean for significant difference", smallest_mean_size, "\n")
}
## 
##  The mean is -> 1 
## The p-value is -> 0.9723208 
## Total signifcant flu cases  0 out of  1 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 11 
## The p-value is -> 0.5224795 
## Total signifcant flu cases  0 out of  2 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 21 
## The p-value is -> 0.9031117 
## Total signifcant flu cases  0 out of  3 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 31 
## The p-value is -> 0.6729678 
## Total signifcant flu cases  0 out of  4 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 41 
## The p-value is -> 0.003393514 
## There is a signifact difference between colder and warmer region flu cases at a mean value of  41 with a p-value of  0.003393514 
## Total signifcant flu cases  1 out of  5 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 51 
## The p-value is -> 0.2015388 
## Total signifcant flu cases  1 out of  6 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 61 
## The p-value is -> 0.8868883 
## Total signifcant flu cases  1 out of  7 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 71 
## The p-value is -> 0.5065441 
## Total signifcant flu cases  1 out of  8 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 81 
## The p-value is -> 0.2471436 
## Total signifcant flu cases  1 out of  9 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 91 
## The p-value is -> 0.1005468 
## Total signifcant flu cases  1 out of  10 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 101 
## The p-value is -> 0.4512696 
## Total signifcant flu cases  1 out of  11 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 111 
## The p-value is -> 0.7483212 
## Total signifcant flu cases  1 out of  12 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 121 
## The p-value is -> 0.05555331 
## Total signifcant flu cases  1 out of  13 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 131 
## The p-value is -> 0.5920528 
## Total signifcant flu cases  1 out of  14 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 141 
## The p-value is -> 0.1834114 
## Total signifcant flu cases  1 out of  15 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 151 
## The p-value is -> 0.9559285 
## Total signifcant flu cases  1 out of  16 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 161 
## The p-value is -> 0.9136589 
## Total signifcant flu cases  1 out of  17 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 171 
## The p-value is -> 0.1705377 
## Total signifcant flu cases  1 out of  18 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 181 
## The p-value is -> 0.830143 
## Total signifcant flu cases  1 out of  19 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 191 
## The p-value is -> 0.3946712 
## Total signifcant flu cases  1 out of  20 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 201 
## The p-value is -> 0.9595559 
## Total signifcant flu cases  1 out of  21 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 211 
## The p-value is -> 0.6939159 
## Total signifcant flu cases  1 out of  22 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 221 
## The p-value is -> 0.9143925 
## Total signifcant flu cases  1 out of  23 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 231 
## The p-value is -> 0.3099618 
## Total signifcant flu cases  1 out of  24 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 241 
## The p-value is -> 0.0679993 
## Total signifcant flu cases  1 out of  25 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 251 
## The p-value is -> 0.8914952 
## Total signifcant flu cases  1 out of  26 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 261 
## The p-value is -> 0.6603441 
## Total signifcant flu cases  1 out of  27 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 271 
## The p-value is -> 0.656667 
## Total signifcant flu cases  1 out of  28 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 281 
## The p-value is -> 0.9425376 
## Total signifcant flu cases  1 out of  29 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 291 
## The p-value is -> 0.3614884 
## Total signifcant flu cases  1 out of  30 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 301 
## The p-value is -> 0.666138 
## Total signifcant flu cases  1 out of  31 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 311 
## The p-value is -> 0.1071825 
## Total signifcant flu cases  1 out of  32 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 321 
## The p-value is -> 0.3561309 
## Total signifcant flu cases  1 out of  33 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 331 
## The p-value is -> 0.6628361 
## Total signifcant flu cases  1 out of  34 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 341 
## The p-value is -> 0.5231457 
## Total signifcant flu cases  1 out of  35 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 351 
## The p-value is -> 0.1577404 
## Total signifcant flu cases  1 out of  36 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 361 
## The p-value is -> 0.7417251 
## Total signifcant flu cases  1 out of  37 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 371 
## The p-value is -> 0.774522 
## Total signifcant flu cases  1 out of  38 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 381 
## The p-value is -> 0.5369836 
## Total signifcant flu cases  1 out of  39 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 391 
## The p-value is -> 0.1074897 
## Total signifcant flu cases  1 out of  40 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 401 
## The p-value is -> 0.1660229 
## Total signifcant flu cases  1 out of  41 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 411 
## The p-value is -> 0.2251047 
## Total signifcant flu cases  1 out of  42 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 421 
## The p-value is -> 0.8297658 
## Total signifcant flu cases  1 out of  43 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 431 
## The p-value is -> 0.2129434 
## Total signifcant flu cases  1 out of  44 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 441 
## The p-value is -> 0.9522409 
## Total signifcant flu cases  1 out of  45 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 451 
## The p-value is -> 0.4761852 
## Total signifcant flu cases  1 out of  46 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 461 
## The p-value is -> 0.8772994 
## Total signifcant flu cases  1 out of  47 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 471 
## The p-value is -> 0.3965405 
## Total signifcant flu cases  1 out of  48 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 481 
## The p-value is -> 0.8326065 
## Total signifcant flu cases  1 out of  49 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 491 
## The p-value is -> 0.1146276 
## Total signifcant flu cases  1 out of  50 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 501 
## The p-value is -> 0.7155539 
## Total signifcant flu cases  1 out of  51 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 511 
## The p-value is -> 0.2260117 
## Total signifcant flu cases  1 out of  52 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 521 
## The p-value is -> 0.2131886 
## Total signifcant flu cases  1 out of  53 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 531 
## The p-value is -> 0.9664006 
## Total signifcant flu cases  1 out of  54 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 541 
## The p-value is -> 0.9116479 
## Total signifcant flu cases  1 out of  55 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 551 
## The p-value is -> 0.7261777 
## Total signifcant flu cases  1 out of  56 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 561 
## The p-value is -> 0.1215297 
## Total signifcant flu cases  1 out of  57 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 571 
## The p-value is -> 0.787963 
## Total signifcant flu cases  1 out of  58 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 581 
## The p-value is -> 0.8898109 
## Total signifcant flu cases  1 out of  59 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 591 
## The p-value is -> 0.3499282 
## Total signifcant flu cases  1 out of  60 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 601 
## The p-value is -> 0.6898711 
## Total signifcant flu cases  1 out of  61 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 611 
## The p-value is -> 0.5550041 
## Total signifcant flu cases  1 out of  62 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 621 
## The p-value is -> 0.1369829 
## Total signifcant flu cases  1 out of  63 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 631 
## The p-value is -> 0.3682489 
## Total signifcant flu cases  1 out of  64 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 641 
## The p-value is -> 0.05658386 
## Total signifcant flu cases  1 out of  65 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 651 
## The p-value is -> 0.9909932 
## Total signifcant flu cases  1 out of  66 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 661 
## The p-value is -> 0.08589805 
## Total signifcant flu cases  1 out of  67 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 671 
## The p-value is -> 0.2367026 
## Total signifcant flu cases  1 out of  68 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 681 
## The p-value is -> 0.8251594 
## Total signifcant flu cases  1 out of  69 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 691 
## The p-value is -> 0.5123982 
## Total signifcant flu cases  1 out of  70 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 701 
## The p-value is -> 0.7583511 
## Total signifcant flu cases  1 out of  71 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 711 
## The p-value is -> 0.528616 
## Total signifcant flu cases  1 out of  72 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 721 
## The p-value is -> 0.07112723 
## Total signifcant flu cases  1 out of  73 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 731 
## The p-value is -> 0.2521965 
## Total signifcant flu cases  1 out of  74 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 741 
## The p-value is -> 0.294557 
## Total signifcant flu cases  1 out of  75 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 751 
## The p-value is -> 0.3535556 
## Total signifcant flu cases  1 out of  76 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 761 
## The p-value is -> 0.6962779 
## Total signifcant flu cases  1 out of  77 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 771 
## The p-value is -> 0.979388 
## Total signifcant flu cases  1 out of  78 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 781 
## The p-value is -> 0.6173703 
## Total signifcant flu cases  1 out of  79 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 791 
## The p-value is -> 0.199368 
## Total signifcant flu cases  1 out of  80 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 801 
## The p-value is -> 0.4823889 
## Total signifcant flu cases  1 out of  81 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 811 
## The p-value is -> 0.3713603 
## Total signifcant flu cases  1 out of  82 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 821 
## The p-value is -> 0.1355641 
## Total signifcant flu cases  1 out of  83 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 831 
## The p-value is -> 0.2582349 
## Total signifcant flu cases  1 out of  84 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 841 
## The p-value is -> 0.8693118 
## Total signifcant flu cases  1 out of  85 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 851 
## The p-value is -> 0.4364386 
## Total signifcant flu cases  1 out of  86 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 861 
## The p-value is -> 0.6631283 
## Total signifcant flu cases  1 out of  87 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 871 
## The p-value is -> 0.6107999 
## Total signifcant flu cases  1 out of  88 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 881 
## The p-value is -> 0.732139 
## Total signifcant flu cases  1 out of  89 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 891 
## The p-value is -> 0.9184461 
## Total signifcant flu cases  1 out of  90 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 901 
## The p-value is -> 0.5337544 
## Total signifcant flu cases  1 out of  91 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 911 
## The p-value is -> 0.6753215 
## Total signifcant flu cases  1 out of  92 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 921 
## The p-value is -> 0.4012866 
## Total signifcant flu cases  1 out of  93 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 931 
## The p-value is -> 0.5789441 
## Total signifcant flu cases  1 out of  94 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 941 
## The p-value is -> 0.5422278 
## Total signifcant flu cases  1 out of  95 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 951 
## The p-value is -> 0.5407129 
## Total signifcant flu cases  1 out of  96 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 961 
## The p-value is -> 0.4782265 
## Total signifcant flu cases  1 out of  97 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 971 
## The p-value is -> 0.8831199 
## Total signifcant flu cases  1 out of  98 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 981 
## The p-value is -> 0.7327152 
## Total signifcant flu cases  1 out of  99 trials 
## Smallest mean for significant difference 351 
## 
##  The mean is -> 991 
## The p-value is -> 0.2966205 
## Total signifcant flu cases  1 out of  100 trials 
## Smallest mean for significant difference 351

Now we will look at altering the standard deviation:

n = mean1
count = 0
smallest_stdev_size = 0

seq_5 <- seq(1, n, by = 5)
seq_10 <- seq(1, n, by = 10)


for (i in 1:length(seq_5)) {
  flu_cases <- (rnorm(n,
                   mean = mean1,
                   sd = seq_5[i]))
  flu_data <- data.frame(flu_cases)
  flu_data$states <- sample(c(1,2), length(flu_cases), replace = TRUE)
  flu_data$variance <- var(flu_cases)
  
  flu_data_aov <- aov(flu_cases~states, data = flu_data)
  flu_data_sum <- summary(flu_data_aov)
  cat("\n","The standard deviation is ->", seq_5[i], "\n")
  cat("The p-value is ->", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
  
  if (i > 1 & count == 0) {
     if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
    smallest_stdev_size = seq_5[i]
     }
  }
  
  if (i > 1) {
    if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
      count = count + 1
     cat("There is a signifact difference between colder and warmer region flu cases at a stdev value of ", smallest_stdev_size, "with a p-value of ", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
      }
    
  }
  cat("Total signifcant flu cases ", count, "out of ", i, "trials", "\n") 
  cat("Smallest standard deviation size for significant difference", smallest_stdev_size, "\n")
}
## 
##  The standard deviation is -> 1 
## The p-value is -> 0.07228899 
## Total signifcant flu cases  0 out of  1 trials 
## Smallest standard deviation size for significant difference 0 
## 
##  The standard deviation is -> 6 
## The p-value is -> 0.9806166 
## Total signifcant flu cases  0 out of  2 trials 
## Smallest standard deviation size for significant difference 0 
## 
##  The standard deviation is -> 11 
## The p-value is -> 0.2216364 
## Total signifcant flu cases  0 out of  3 trials 
## Smallest standard deviation size for significant difference 0 
## 
##  The standard deviation is -> 16 
## The p-value is -> 0.5157431 
## Total signifcant flu cases  0 out of  4 trials 
## Smallest standard deviation size for significant difference 0 
## 
##  The standard deviation is -> 21 
## The p-value is -> 0.3383277 
## Total signifcant flu cases  0 out of  5 trials 
## Smallest standard deviation size for significant difference 0 
## 
##  The standard deviation is -> 26 
## The p-value is -> 0.4261707 
## Total signifcant flu cases  0 out of  6 trials 
## Smallest standard deviation size for significant difference 0
count = 0


for (i in 1:length(seq_10)) {
  flu_cases <- (rnorm(n,
                   mean = mean1,
                   sd = seq_10[i]))
  flu_data <- data.frame(flu_cases)
  flu_data$states <- sample(c(1,2), length(flu_cases), replace = TRUE)
  flu_data$variance <- var(flu_cases)
  
  flu_data_aov <- aov(flu_cases~states, data = flu_data)
  flu_data_sum <- summary(flu_data_aov)
  cat("\n","The standard deviation is ->", seq_10[i], "\n")
  cat("The p-value is ->", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
  
  if (i > 1 & count == 0) {
     if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
    smallest_stdev_size = seq_10[i]
     }
  }
  
  if (i > 1) {
    if (flu_data_sum[[1]]$`Pr(>F)`[1] < 0.05) {
      count = count + 1
     cat("There is a signifact difference between colder and warmer region flu cases at a stdev value of ", seq_10[i], "with a p-value of ", flu_data_sum[[1]]$`Pr(>F)`[1], "\n")
      }
    
  }
  cat("Total signifcant flu cases ", count, "out of ", i, "trials", "\n") 
  cat("Smallest standard deviation size for significant difference", smallest_stdev_size, "\n")
}
## 
##  The standard deviation is -> 1 
## The p-value is -> 0.449475 
## Total signifcant flu cases  0 out of  1 trials 
## Smallest standard deviation size for significant difference 0 
## 
##  The standard deviation is -> 11 
## The p-value is -> 0.5778109 
## Total signifcant flu cases  0 out of  2 trials 
## Smallest standard deviation size for significant difference 0 
## 
##  The standard deviation is -> 21 
## The p-value is -> 0.7692925 
## Total signifcant flu cases  0 out of  3 trials 
## Smallest standard deviation size for significant difference 0

Looking back at our original data, set up at the top, what is the smallest sample size I could do to get a significant value?

After numerous runs, the best I got was a sample size of 40, but this was due to random generation, you can see that we run it with 40 as the sample size, we might not repeat this result. Side note - this is why set.seed is helpful for sharing code/data so we can repeat results. In this example, we are working with random data every time

flu_cases <- (rnorm(40,
                   mean = mean1,
                   sd = stdev1))
  flu_data <- data.frame(flu_cases)
  flu_data$states <- sample(c(1,2), length(flu_cases), replace = TRUE)
  flu_data$variance <- var(flu_cases)
  
  flu_data_aov <- aov(flu_cases~states, data = flu_data)
  flu_data_sum <- summary(flu_data_aov)
  flu_data_sum
##             Df Sum Sq Mean Sq F value Pr(>F)
## states       1   11.1   11.14   0.757   0.39
## Residuals   38  559.7   14.73

We can see all in all that through manipulation of mean and sample size, we notice about 5-15% of the runs will result in a significant difference of flu cases between warmer and colder regions. Switching standard deviation gives us about 0-33% of the runs result in significant difference.